Microsoft Copilot alternatives for chat and files
Compare LibreChat, Open WebUI and Cherry Studio for chat and file analysis, plus GPTLocalhost for AI inside Word documents.
Microsoft Copilot answers questions, helps with writing and analyzes material in chat. Microsoft also connects Copilot to work in its productivity apps, so replacing the conversational assistant and replacing that app integration are separate decisions. The tools below concentrate on chat, files and a few clearly scoped document workflows.
LibreChat and Open WebUI offer shared chat workspaces with file tasks and connected tools. Cherry Studio provides desktop conversations with Office files and PDFs. Khoj adds document search and web research, while GPTLocalhost brings model-backed work into Word itself. Nextcloud Assistant covers documents, email and calendar in Nextcloud Hub; it does not reproduce Copilot inside Microsoft 365.
Self-hosted office suite for collaborative document editing with local AI models. Free and open source under AGPL-3.0, with Docker, Linux and Windows support.

A self-hosted AI assistant for Nextcloud Hub handles documents, chat and calendar tasks with local models or cloud providers under AGPL-3.0.

Nextcloud Assistant summarizes mail and chat, rewrites documents and answers questions about files inside Nextcloud Hub. It suits teams moving their productivity workflow to Nextcloud, with the available AI tasks depending on configured providers.
A self-hosted AI assistant uses Ollama or cloud models to search documents and automate tasks, with native apps for Windows, macOS and Linux.

An AI client for Microsoft Word that lets you use your choice of local or cloud language models.

GPTLocalhost connects Microsoft Word to a separate local model server or cloud provider. Document generation, translation and dialogue across documents make it relevant specifically to Copilot-in-Word work; it does not cover Excel or Outlook integration.
A self-hosted AI search and chat platform that connects company knowledge to employees and agents, with local model support and air-gapped deployment.

Onyx covers questions about company knowledge spread across workplace apps. Its search checks source permissions, and agents can turn findings into reports or downloadable documents. This is workplace search and research rather than editing inside Office.
A self-hosted AI chat platform connects local models and cloud APIs, with tool-using agents, conversation search and multi-user authentication.

LibreChat covers multi-provider chat, uploaded-file work and assistants that execute code or use connected tools. It suits Copilot users who want one self-hosted conversation workspace, including teams sharing agents and controlling access.
An open-source desktop AI chat app for Windows, macOS and Linux that connects to local models through Ollama or LM Studio and to cloud providers.

A desktop AI assistant reads screen context on Windows and macOS, works with local models through Ollama, and uses MCP tools to carry out tasks.

A self-hosted workplace AI platform searches connected business apps with source permissions and cited answers, using local models through Ollama or cloud APIs.

A self-hosted AI chat interface that works offline with local models and connects to Ollama, OpenAI-compatible APIs and cloud providers.

A self-hostable AI assistant that searches documents and the web, supports local or online LLMs, and runs custom agents and scheduled automations.

Khoj searches your documents and the web, supports custom agents and schedules recurring research. It suits replacing Copilot questions that depend on personal files or outside information, with local or online model choices.
An open-source AI data analysis workspace that runs locally in your browser or Docker, with Ollama support and editable charts. MIT licensed.

Data Formulator covers spreadsheet analysis with natural-language questions and editable charts. Its Data Thread keeps tables and explanations beside each result, with branches for alternative investigations. It is a separate analysis workspace rather than an Excel add-in.
A self-hosted AI data assistant that writes SQL, analyzes spreadsheets, and produces reports using privately deployed models or cloud APIs.
A self-hosted AI knowledge platform combines cited document Q&A, agent tasks and linked wiki pages, with Ollama inference and offline deployment support.

WeKnora provides cited document answers and agent tasks in a team knowledge workspace. Scoped access, identity connections and audit logs govern that work; its documented source integrations include Confluence, GitLab, Notion and Feishu.
An AI email assistant for Thunderbird that drafts and organizes messages using local models through Ollama or LM Studio, or cloud services.

ThunderAI covers email drafting and inbox triage inside Thunderbird. It summarizes messages, suggests tags and applies classification rules, with reviewable proofreading for replies. It serves the mail workflow in Thunderbird rather than Outlook.
For Microsoft Copilot, start with ONLYOFFICE Docs. Other alternatives include Nextcloud Assistant, OpenAgent, GPTLocalhost and Onyx.
Most are Chat With Your Documents; others include Personal AI Assistants.